The Membertou First Nation is a Mi'kmaq First Nation located in the tribal district of Unama'ki, also known as Cape Breton Island, Nova Scotia. As of 2012, the Mi'kmaq population is 814 on-Reserve, and approximately 481 off-Reserve. The First Nation was named after the Grand Chief Henri Membertou (1510-1611) the Membertou First Nation belongs to the greater tribal group of the Mi'kmaq Nation.